Johanne MATSUBARA, PhD
Professor. Dept of Ophthalmology and Visual Sciences
Faculty Lead, UBC Research Excellence Cluster in Vision
University of British Columbia
Vancouver, BC, CANADA
Biographie/Biography
I am a Professor in Ophthalmology and Visual Sciences with over 25 years of experience in basic and translational research on neurodegenerative diseases of the eye and brain. Using cell culture and animal models, my work focuses on understanding the early cellular and molecular triggers of neuroinflammation and retinal degeneration, particularly in the wet and dry forms of age-related macular degeneration (AMD). My translational, collaborative, and interdisciplinary work focuses on developing novel small-molecule drugs, advanced ocular drug delivery methods, and next-generation in vivo retina imaging for preclinical drug therapy assessment. Our team also develops fluorescent probes for in vivo visualization of retinal amyloid beta deposits to understand the ocular manifestations of Alzheimer’s disease in mouse models. As the Lead Investigator of UBC’s Vision Sciences Research Excellence Cluster and a former department Director of Research, I have fostered cross-disciplinary collaborations across fields such as molecular and cellular biology, chemistry, computer sciences, biomedical engineering and entrepreneurship.
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Résumé/Abstract
Titre: A venir
Résumé: A venir