Jason FISH, Ph.D.
Professor, Laboratory Medicine and Pathobiology, University of Toronto
Senior Scientist, University Health Network
Toronto, ONT, CANADA
Biographie/Biography
Dr. Jason Fish completed his PhD at the University of Toronto under the supervision of Dr. Philip Marsden. Here he uncovered a role for epigenetics in gene regulation in blood vessels. This was followed by a postdoctoral fellowship at the Gladstone Institute of Cardiovascular Disease and the University of California San Francisco under the supervision of Dr. Deepak Srivastava. Here, Dr. Fish uncovered a role for microRNAs in regulating the development of the cardiovascular system. Since moving back to Toronto in 2010, Dr. Fish and his team explore the mechanisms of gene regulation in the endothelium in health and disease. His recent work has uncovered how somatic mutations in the endothelium lead to sporadic brain arteriovenous malformations, a leading cause of stroke in young people. His laboratory is uncovering the mechanisms involved and is using this information to design new therapies. Dr. Fish’s laboratory is also determining how chemotherapy affects the vascular system and how altered endothelial cell identity contributes to atherosclerosis.
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Résumé/Abstract
Titre: A venir
Résumé: A venir